In combination of free radical
scavenger and metal chelator, the chelator decreases the oxidation rates
by inhibiting metal-catalyzed oxidation; resulting in, fewer free
radicals generated in the system. Inactivation of antioxidants via
termination reaction or participation in autoxidation occurs to a lesser
extent in such situations. The concentration of antioxidant, available
to scavenge free radicals, will always be greater at a given time than
when no metal chelator is present. The combination of chelator and
radical scavenger decreases free radical generation and increases
radical scavenging potential . Synergistic activity has been observed in
the mixtures of natural tocopherols and citric acid. The synergistic
effect of this mixture is caused by the chain-breaking ability of
tocopherols and metal chelation of citric acid .
E. N. Frankel, Lipid Oxidation, The Oily Press, West Ferry, Dundee, 1998, pp. 13, 79, 115, 129, and 167.
E. A. Decker, in C. C. Akoh and D. B. Min, eds., Food Lipids: Chemistry, Nutrition and Biotechnology, 2nd ed., Marcel Dekker, Inc., New York, 2002, p. 517.
E. N. Frankel, Lipid Oxidation, The Oily Press, West Ferry, Dundee, 1998, pp. 13, 79, 115, 129, and 167.
E. A. Decker, in C. C. Akoh and D. B. Min, eds., Food Lipids: Chemistry, Nutrition and Biotechnology, 2nd ed., Marcel Dekker, Inc., New York, 2002, p. 517.
Green tea polyphenol (-)-epigallocatechin-3-gallate treatment of human skin inhibits ultraviolet radiation-induced oxidative stress.
Protective effects of EGCG on UVB-induced damage in living skin equivalents.
Treatment of green tea polyphenols in hydrophilic cream prevents UVB-induced oxidation of lipids and proteins, depletion of antioxidant enzymes and phosphorylation of MAPK proteins in SKH-1 hairless mouse skin.
Fucoidan inhibits UVB-induced MMP-1 promoter expression and down regulation of type I procollagen synthesis in human skin fibroblasts
Sclerotium rolfsii scleroglucan: the promising behavior of a natural polysaccharide as a drug delivery vehicle, suspension stabilizer and emulsifier.
Ferulic Acid Stabilizes a Solution of Vitamins C and E and Doubles its Photoprotection of Skin
Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo.
Scleroglucan: A Versatile Polysaccharide for Modified Drug Delivery
Ingredients | % required |
L Ascorbic acid | 15 % |
Vitamin E Oil | 1% |
Ferulic acid | 0.5 % |
Sea Emollient | 28% |
EGCG /Green Tea Extract | 5% |
Sclerotium Gum | 2% |
Distilled Water | 40.5% |
1 N NaOH | 2% |
Citric Acid | 0.5% |
Oil of Choice | 5 % |
Phenoxyethanol | 0.5% |
1. Weigh and measure your ingredients.
2. Ferulic acid into solution with NaOH or ETOH, stir till dissolved = white
3. LAA into water, stir till dissolved, may have some light dust, don't panic.
4. EGCG into LAA and Water Stir, Will turn a honey color tan/ brown
5. Citric acid into mix, stir/ blend
6. Sclerotium gum , mix and blend
7. Sea emollient, blend
8. Vit E oil, Oil of choice + Phenoxy
9. Adjust pH to 3.2 or under.
Creates an ultra light and silky serum.